Tag Archives: Systematic Reviews

Delayed Cord Clamping re-re-visited

Posted on 4 June 2015 by Keith Barrington

I have been trying to develop some sort of protocol for babies in our center, so I have been reading in some detail the studies about very preterm births and cord clamping that are in the literature. It seems from … Continue reading →

Posted in Neonatal Research | Tagged , , , | 3 Comments

Delayed cord clamping or cord milking for the very preterm newborn… or both?

Posted on 18 May 2015 by Keith Barrington

What should we be doing, given the current state of the evidence, for the very preterm neonate? I think the evidence is now pretty clear that full-term babies have benefits, and no significant harm, from delayed cord clamping, which has … Continue reading →

Posted in Neonatal Research | Tagged , , , , | 9 Comments

Probiotics: so what about those ELBW babies?

Posted on 24 September 2014 by Keith Barrington

After a comment to my previous post about probiotics, I wanted to clarify what I said about the ELBW baby, that is, the newborn with a birth weight below 1001 grams. It is true that there are few studies that … Continue reading →

Posted in Neonatal Research | Tagged , , , | 4 Comments

The Time for a Confirmative Necrotizing Enterocolitis Probiotics Prevention Trial in the Extremely Low Birth Weight Infant in North America Is Well Past

Posted on 23 September 2014 by Keith Barrington

What on earth are these people waiting for? A number of authors from Toronto and elsewhere have written a ridiculous editorial (entitled ‘The Time for a Confirmative Necrotizing Enterocolitis Probiotics Prevention Trial in the Extremely Low Birth Weight Infant in … Continue reading →

Posted in Neonatal Research | Tagged , , , | 3 Comments

Retraction of a systematic review

Posted on 28 April 2014 by Keith Barrington

Exactly when should an article be retracted? That is not so easy a question to answer, fraud and significant data or image manipulation are one fairly obvious group of reasons. Making errors and/or poor research design are more tricky. When … Continue reading →

Posted in Neonatal Research | Tagged , , | Leave a comment

Resuscitating preterm infants: how many O’s

Posted on 21 April 2014 by Keith Barrington

Very often in neonatology (and in life) we have to make a decision based on inadequate data. For example, when resuscitating a very preterm baby you have to decide where to set the starting FiO2, even if there are no … Continue reading →

Posted in Neonatal Research | Tagged , , , , | Leave a comment

Three new publications

Posted on 27 January 2014 by Keith Barrington

The latest issue of Seminars in Perinatology has just appeared on line. This is second part of the report of the NICHD, SMFM, ACOG, AAP joint workshop where Annie and I presented. I think these articles are all free access: … Continue reading →

Posted in Neonatal Research | Tagged , , , | Leave a comment

NIDCAP, battling systematic reviews.

Posted on 7 January 2014 by Keith Barrington

I mentioned Arne Ohlsson’s review of the NIDCAP studies in a previous post. A new systematic review comes to different conclusions. This review (Fazilleau L, Parienti JJ, Bellot A, Guillois B: Nidcap in preterm infants and the neurodevelopmental effect in … Continue reading →

Posted in Neonatal Research | Tagged | Leave a comment

Reducing BPD by Avoiding Intubation

Posted on 29 October 2013 by Keith Barrington

Sometimes more than one article gets published almost simultaneously on the same topic, sometimes with similar methodology. Two systematic reviews of the effects of trying to avoid or curtail endotracheal intubation in order to protect the lungs have just been … Continue reading →

Posted in Neonatal Research | Tagged , , , , | 1 Comment

Pain hurts

Posted on 21 October 2013 by Keith Barrington

In 2010 a paper published in the Lancet called into question the use of sucrose as an analgesic for heelsticks. (I will use the US term as I think most people understand that it refers to lancing the heel of … Continue reading →

Posted in Neonatal Research | Tagged , , , , , | 8 Comments