Tag Archives: Platelets

On which Planet? Reducing platelet transfusions in the newborn.

Posted on 24 October 2023 by Keith Barrington

Recent publications about platelet transfusions in the newborn. Hopefully, everyone has integrated the findings of Planet-2 into their protocols and guidelines. Curley A, et al. Randomized Trial of Platelet-Transfusion Thresholds in Neonates. N Engl J Med. 2019;380(3):242-51. This trial, in … Continue reading →

Posted in Neonatal Research | Tagged , , | 2 Comments

Platelet transfusion threshholds: 25,000 even for the highest risk infants?

Posted on 6 December 2019 by Keith Barrington

The Planet-2 trial that I posted about when it first came out showed no benefit among preterm infants, <34 weeks gestation when they received platelet transfusions at a threshold of 50,00 compared to waiting until they dropped to 25,000. I … Continue reading →

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Platelet transfusions don’t close the PDA, but they may increase IVH

Posted on 13 April 2019 by Keith Barrington

I would never have actually thought to ask the question whether platelet transfusion might close the PDA, although early thrombocytopenia is associated with persistent PDA, and platelet plugs seem to be part of the mechanism of closure. A group in … Continue reading →

Posted in Neonatal Research | Tagged , , , | 2 Comments