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Meta
Tag Archives: infection control
TPN toxic?
Humans, after they are born, are supposed to receive their nutrition via the gut. Before that of course, they receive a continuous infusion of nutrition via the umbilical vein. We are far from having an intravenous nutrition mixture for sick … Continue reading
Posted in Neonatal Research
Tagged infection control, nutrition, Randomized Controlled Trials, Sepsis
1 Comment
Lacuna trial now in print
Now available on-line the pilot trial of lactoferrin prophylaxis that I performed at Sainte Justine. (Barrington KJ, Assaad M-A, Janvier A. The Lacuna Trial: a double-blind randomized controlled pilot trial of lactoferrin supplementation in the very preterm infant. J Perinatol. … Continue reading
Posted in Neonatal Research
Tagged infection control, Randomized Controlled Trials, Sepsis
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Preventing and Treating Sepsis in Preterm Babies
These two studies are both issues that I am involved with, Theresa Ochoa’s study I was aware of, and was waiting for the full publication, the other, from Egypt, I didn’t know about but should have done, but it confirms … Continue reading
At least they weren’t worse off.
Fever is a frequent response to infection. The inflammatory response to invading organisms often leads to a febrile reaction, which many have suggested is an adaptive response, that might actually have an evolutionary advantage, and improve survival from serious infections. Of course … Continue reading
Keeping Central Lines clean, very clean.
Shepherd EG, et al. Significant Reduction of Central-Line Associated Bloodstream Infections in a Network of Diverse Neonatal Nurseries. The Journal of pediatrics. 2015. This is an observational study from a group which includes a large number of neonatal beds. They … Continue reading
Sense about Sepsis
Recent guidelines regarding the evaluation and treatment of early onset sepsis, or the baby who has risk factors, have been widely criticized. Especially by me! And by me! The AAP for example recommends antibiotic treatment for all infants born after … Continue reading
Let’s scrub those hubs!
‘Scrub the hub’ is a part of many catheter sepsis prevention bundles. The idea being that organisms can be introduced into the infusion solution from inadequate cleaning of connectors, so 15 seconds minimum of vigorous application of alcohol wipes should … Continue reading
Effects of (not very) NICE guidelines
Call me prescient, OK, you won’t, but I will. Two recent observational studies suggest that the recent NICE guidelines have had adverse effects on infants evaluated for potential early neonatal sepsis. ‘NICE’ of course is not an adjective for how good … Continue reading
Gastric acid is good for you
I might have used that title previously, but new data published in JAMAPediatrics supports the concept. In a prospective cohort study the authors cultured fluid from gastroscopies, and bronchoscopies in children, and compared the results between those who were on … Continue reading
Should we all be wearing gloves? Every time we touch a baby?
Two new articles over the summer suggest that the answer to that question may well be yes. The first is the best quality of the studies, an RCT in a single center in the USA. Kaufman DA, Blackman A, Conaway MR, Sinkin … Continue reading
Posted in Neonatal Research
Tagged infection control, Randomized Controlled Trials, Sepsis
2 Comments
Neonatal Research 