Category Archives: Neonatal Research

PDA shunts and extubation

Posted on 12 December 2013 by Keith Barrington

Following on from my recent post about PEEP levels and PDA shunts, this new article from Perth. The authors prospectively enrolled very immature infants (< 28 weeks) before a planned early extubation and did echocardiograms before and after. The mean … Continue reading →

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Omega 3 containing lipid emulsions for the preterm: time for a large RCT

Posted on 11 December 2013 by Keith Barrington

A recent small RCT from Turkey, n=80 (Beken S, Dilli D, Fettah ND, Kabatas EU, Zenciroglu A, Okumus N: The influence of fish-oil lipid emulsions on retinopathy of prematurity in very low birth weight infants: A randomized controlled trial. Early … Continue reading →

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PEEP and ductal shunts

Posted on 9 December 2013 by Keith Barrington

I never thought that modest increase in PEEP would have a real effect on ductal shunting. As the size of the ductal shunt depends on the pressure gradient across the PDA and the resistance of the vessel, in order to … Continue reading →

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Acid suppression doesn’t work, and it’s not safe. pHunny how we got here.

Posted on 6 December 2013 by Keith Barrington

Maybe it’s not pHunny at all. A good quality review article about the use of acid blockade for treating what are sometimes called ‘symptoms of reflux’. Rosen R: Gastroesophageal reflux in infants: More than just a pHenomenon. JAMA Pediatrics 2013. … Continue reading →

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Neonatal Updates: back after brief blogging break

Posted on 4 December 2013 by Keith Barrington

After a trip to Europe for ongoing planning for the HIP trial, (link on the side bar) and several days getting over the jet-lag and trying to catch up, I am ready to get going again. So here is my … Continue reading →

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Why we care

Posted on 28 November 2013 by Keith Barrington

Many of you will have already seen this video, but watch it anyway. I hesitated before putting this link, as every time I watch this it brings back painful, but wonderful memories. Anyway, this is why we do what we … Continue reading →

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Parents advocate for equality for preterm infants

Posted on 27 November 2013 by Keith Barrington

The president of the Canadian Premature Babies Foundation, Katharina Staub, has just had a letter published in the CMAJ. The letter was in response to the article by Dan and Beau Batton, and emphasizes many of the points that they … Continue reading →

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Probiotics work, they really, really, work! (And they are safe)

Posted on 22 November 2013 by Keith Barrington

The Proprems study that I have referred to a couple of times before has now been published. This was a multicenter RCT of a probiotic preparation in 1100 very preterm infants less than 1500 grams and less than 32 weeks. … Continue reading →

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GE Reflux… again

Posted on 22 November 2013 by Keith Barrington

Esomeprazole is one of the Proton pump inhibitors that is quite effective at reducing gastric acid production. This RCT of 51 infants (preterms to 1 month of age) randomized babies that had symptoms that were interpreted as being due to … Continue reading →

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Personalized Medicine in the NICU

Posted on 20 November 2013 by Keith Barrington

An article I wrote, with that title, as an open peer commentary in the American Journal of Bioethics has just appeared on-line. The first 50 people to click on the link at the bottom of this post below can get a free full … Continue reading →

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