Author Archives: Keith Barrington

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About Keith Barrington

I am a neonatologist and clinical researcher at Sainte Justine University Health Center in Montréal

Gastro-esophageal Reflux, are we thick enough?

Posted on 21 December 2012 by Keith Barrington

Making the milk thicker, in order to make it harder to reflux, has a long history in the treatment of GE reflux, or spitting-up babies. As I mentioned in a previous post there are some thickeners that have been associated … Continue reading →

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Probiotics: more than enough!

Posted on 21 December 2012 by Keith Barrington

Yet another small RCT of probiotics. This time 150 infants less than 1500 grams birth weight in an NICU in Mexico were randomized to a mixture of 4 different Lactobacilli and Bifidobacterium infantis or control. There was a reduction in … Continue reading →

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Reducing Global Neonatal Mortality

Posted on 21 December 2012 by Keith Barrington

Melinda Gates has written a column in the Economist where she notes that the improvements in child and maternal mortality seen in response to the millennium development goals have not been reflected in reductions in neonatal mortality. The column is short, … Continue reading →

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Weekly Updates #18

Posted on 21 December 2012 by Keith Barrington

Abbas W, Attia NI, Hassanein SM: Two-stage single-volume exchange transfusion in severe hemolytic disease of the newborn. The journal of maternal-fetal & neonatal medicine. 2012, 25(7):1080-1083. In this randomized clinical trial the authors did 104 exchange transfusions, they randomized the … Continue reading →

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Is the glass 81% full or 19% empty?

Posted on 17 December 2012 by Keith Barrington

The new Epicure 2 data show encouraging trends in outcomes in the UK and Ireland for extremely preterm babies. Survival rates have improved significantly over the whole of the British Isles, Here for example is one of the figures from … Continue reading →

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I am Epicurious…

Posted on 14 December 2012 by Keith Barrington

Two publications have just appeared from the EPICURE 2 study. The first (Costeloe KL, Hennessy EM, Haider S, Stacey F, Marlow N, Draper ES: Short term outcomes after extreme preterm birth in England: comparison of two birth cohorts in 1995 … Continue reading →

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Weekly Updates #17

Posted on 7 December 2012 by Keith Barrington

Moon C, Lagercrantz H, Kuhl PK: Language experienced in utero affects vowel perception after birth: A two-country study. Acta Paediatrica 2012. This is neat, the researchers played recordings of different vowel sounds to Swedish and American babies who were just … Continue reading →

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One Babe at a Time: ART and a multiplicity of multiples

Posted on 7 December 2012 by Keith Barrington

I have just written a review article which is in the submission revision process for a journal that shall remain nameless (I don’t know why, but that is the tradition, you don’t say which journal, until it gets accepted) It … Continue reading →

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Weekly Updates #16

Posted on 1 December 2012 by Keith Barrington

Sarajuuri A, Jokinen E, Mildh L, Tujulin A-M, Mattila I, Valanne L, Lönnqvist T: Neurodevelopmental burden at age 5 years in patients with univentricular heart. Pediatrics 2012. This study followed infants with univentricular lesions, both hypoplastic left heart syndrome and … Continue reading →

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New agents for hemodynamic support; how to evaluate them?

Posted on 1 December 2012 by Keith Barrington

I have only ever prescribed a vasopressin infusion once for a baby. An infant was dying of septic shock and I done everything that I thought might help, without any evident benefit. So I decided to try vasopressin, based on … Continue reading →

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