Bugs in the news

Many thanks to Girish Deshpande for sending me a link to an Australian news item about probiotics and their use in the preterm, a 2 minute video clip for your edification.

http://www.abc.net.au/news/2013-04-10/new-hope-for-premature-babies/4619984

The excellent science blogs ‘Phenomena’ have an article about probiotics, not at all neonatal, but talking about the overall importance of microbiome manipulation for the future.

I spoke about the science of probiotics in Atlanta 2 days ago at the organization of Georgia neonatologists, Annie followed with a talk about the politics of probiotics, which was of course the title of a recent article that we published with John Lantos.

I usually think of the GI microbiome in terms of what bugs are in the colon, this new article (Milisavljevic V, Garg M, Vuletic I, Miller J, Kim L, Cunningham T, Schroder I: Prospective assessment of the gastroesophageal microbiome in vlbw neonates. BMC Pediatrics 2013, 13(1):49). analyzed the microbiome of the stomach and esophagus in very preterm infants in an NICU, many of the samples grew germs and they were not very nice ones. Coagulase negative staph and a range of potentially pathogenic Gram negative organisms were found.

We cannot keep the gut of the preterm baby sterile. Encouraging colonization with good probiotic organisms, several of which, with good quality control, are available in the USA and elsewhere in the world, is both rational and evidence based. ABCDophilus, used in the recently completed and positive ProPrems trial is actually made in the USA.

About keithbarrington

I am a neonatologist and clinical researcher at Sainte Justine University Health Center in Montréal
This entry was posted in Neonatal Research and tagged , . Bookmark the permalink.

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s