Tag Archives: Sepsis

Cohort study of Probiotics in our NICU

Our article describing the results of introducing routine probiotic prophylaxis in our NICU has just become available on-line. Janvier A, Malo J, Barrington KJ: Cohort Study of Probiotics in a North American Neonatal Intensive Care Unit. The Journal of pediatrics … Continue reading

Posted in Neonatal Research | Tagged , , | 2 Comments

Maybe CRPs are not CRaP? Not entirely convinced yet.

This is  a nicely done study, with interesting data, but I am not sure I agree 100% with the conclusions. Lots of newborn babies get antibiotics for suspected infection, they are usually stopped at 48 hours if the cultures are negative, … Continue reading

Posted in Neonatal Research | Tagged | 1 Comment

Is cows milk just for cows?

A new publication from the trial funded by Prolacta looking at possible benefits of their donor-human-milk derived preparations. This time it is the other comparison from the registered trial. That is; mothers who did not plan to breast feed were approached to … Continue reading

Posted in Neonatal Research | Tagged , , , , | Leave a comment

Susceptibility to Sepsis

It looks like those Toll-like receptors may indeed be important. I included a review article in a previous Neonatal Updates, which was nice introduction to these transmembrane receptors that are important in immune responses. A new article suggests that variants … Continue reading

Posted in Neonatal Research | Tagged , , | Leave a comment

NICE! Or mostly so… treatment of early onset neonatal infection

The National Institute of Clinical Excellence in the UK has been a real boon to the NHS, despite attempts to limits its influence by the pharmaceutical companies, the explicit evaluation of risks and benefits of various interventions allows appropriate use … Continue reading

Posted in Neonatal Research | Tagged , | 5 Comments

Early Detection of Sepsis in the NICU

This came out before I started my blog, but think it is very important. I was reminded that I had never mentioned it on this blog when I met Joseph Randall Moorman at the airport on the way back from … Continue reading

Posted in Neonatal Research | Tagged , | Leave a comment

What is heteroresistance?

Recent cases of coagulase negative staphylococci, that were very difficult to eradicate, have led to an assessment of whether the phenomenon of heteroresistance may play a part. To be honest, for me this is entirely new; I was not aware … Continue reading

Posted in Neonatal Research | Tagged , | 1 Comment

Septic Shock

This study is not neonatal at all, not even pediatric, but I think it is really important. Ranieri VM, Thompson BT, Barie PS, Dhainaut JF, Douglas IS, Finfer S, et al. Drotrecogin Alfa (Activated) in Adults with Septic Shock. N … Continue reading

Posted in Neonatal Research | Tagged , | Leave a comment