Tag Archives: Sepsis

Nosocomial infections, “Hospital-Acquired Infections”, and now “Hospital-Onset Bacteremia”

Posted on 7 August 2024 by Keith Barrington

It has been clear for a while that the focus of some groups and some publications on only infections associated with central venous catheters, so-called CLABSI, was missing the point. You could completely eliminate CLABSI by not using central lines, … Continue reading →

Posted in Neonatal Research | Tagged , , | Leave a comment

Intravenous Nutrition of the sick term and late preterm infants : part 2.

Posted on 17 May 2024 by Keith Barrington

The other trial is a much larger multicentre trial with clinical outcomes. (Alexander T, et al. Nutritional Support for Moderate-to-Late-Preterm Infants – A Randomized Trial. N Engl J Med. 2024;390(16):1493-504), the gestational ages only overlapped by 1 week with the … Continue reading →

Posted in Neonatal Research | Tagged , , | 2 Comments

Intravenous Nutrition of sick term and late preterm infants : part 1.

Posted on 16 May 2024 by Keith Barrington

There are 2 new trials addressing different aspects of the questions surrounding what to do about TPN for this group of babies. My readers may remember my post about the PEPaNIC trial, which showed that there were disadvantages of early … Continue reading →

Posted in Neonatal Research | Tagged , , | 2 Comments

How should we pasteurize donor breast milk?

Posted on 23 April 2024 by Keith Barrington

The standard method of pasteurization of donor breast milk, and I believe the only method approved by HMBANA (the human milk banking association of north america), is similar to what Louis Pasteur himself came up with a couple of centuries … Continue reading →

Posted in Neonatal Research | Tagged , , , , | 1 Comment

Do probiotics only work in bigger babies? What is the risk-benefit of routine probiotics in the extremely preterm?

Posted on 13 November 2023 by Keith Barrington

The recent statement from the AAP and a recent review article both state that probiotics only appear to be effective in babies over 1000g birthweight. This would be remarkable if it were true. I am trying to think of another … Continue reading →

Posted in Neonatal Research | Tagged , , , , , | 1 Comment

Interesting study, impossible results. Donor breast milk is not toxic.

Posted on 29 October 2023 by Keith Barrington

Is it possible that giving artificial formula to babies will prevent 90% of the deaths of very preterm babies, compared to using donor human milk? (Chehrazi M, et al. Outcomes in very preterm infants receiving an exclusive human milk diet, … Continue reading →

Posted in Neonatal Research | Tagged , , , | 6 Comments

The preterm GI tract is not sterile

Posted on 27 October 2023 by Keith Barrington

The FDA are at it again, they seem to be on a mission to go after suppliers of probiotics for preterm babies, and have now attacked Abbott. They appear to have demanded that they stop marketing their probiotic product, as … Continue reading →

Posted in Neonatal Research | Tagged , , , , , | 4 Comments

Preventing NEC : Gastric acid has a purpose, don’t block it.

Posted on 13 October 2023 by Keith Barrington

As this series of posts have all had something to do with prevention of Necrotising Enterocolitis, I thought I’d write about some recent articles which refer to one of the risk factors for NEC, the use of acid suppression medications. … Continue reading →

Posted in Neonatal Research | Tagged , , , | 2 Comments

The myth of the “exclusive human milk diet”; fortification options for breast milk.

Posted on 12 October 2023 by Keith Barrington

The Exclusive Human Milk Diet sounds superficially immediately convincing: “We should only give milk products derived from human milk to human babies”. But, is it more than just a catchy phrase? The major company which is responsible for producing a … Continue reading →

Posted in Neonatal Research | Tagged , , , , , | 11 Comments

Probiotics. What now?

Posted on 6 October 2023 by Keith Barrington

Many of you will have seen or heard of the FDA warning about probiotics in preterm infants. In a letter (I am not in the USA, so I am not sure exactly who this letter was sent to, or the … Continue reading →

Posted in Neonatal Research | Tagged , , , , , | 6 Comments