Tag Archives: Necrotising Enterocolitis

Therapeutic Hypothermia: not a panacea

Posted on 11 October 2013 by Keith Barrington

If hypothermia protects the brain, maybe we should use it for anyone who is at risk of brain injury during acute illness? Fortunately other potential uses of hypothermia are being investigated, such as this:  Mourvillier B, Tubach F, van de Beek D, … Continue reading →

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The Microbiome and NecrotiSing Enterocolitis

Posted on 6 October 2013 by Keith Barrington

Fortunately Pubmed speaks both English and American, if you search on Pubmed for necrotizing enterocolitis it also gives you articles about correctly spelt gut diseases in preterm infants as well. As a North American transplant my spelling has become a … Continue reading →

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Prebiotics, to support growth of Probiotics, and how to kill them

Posted on 25 September 2013 by Keith Barrington

Ishizeki S, Sugita M, Takata M, Yaeshima T: Effect of administration of bifidobacteria on intestinal microbiota in low-birth-weight infants and transition of administered bifidobacteria: A comparison between one-species and three-species administration. Anaerobe 2013, 23(0):38-44. In this study the investigators report 3 … Continue reading →

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Is cows milk just for cows?

Posted on 26 August 2013 by Keith Barrington

A new publication from the trial funded by Prolacta looking at possible benefits of their donor-human-milk derived preparations. This time it is the other comparison from the registered trial. That is; mothers who did not plan to breast feed were approached to … Continue reading →

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We didn’t find what we wanted to find, so we thought we’d re-analyze the data until we found it.

Posted on 26 August 2013 by Keith Barrington

…oh and by the way, we are the manufacturers making the product in question, so we had objective scientific reasons for doing this, no conflict of interest whatever. The commercial sponsors of a negative trial decided that they didn’t like … Continue reading →

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Nutritional Catch-Up

Posted on 19 August 2013 by Keith Barrington

This is my attempt to catch up with some interesting publications from the last few weeks, about nutritional interventions and necrotizing enterocolitis. Karagol BS, Zenciroglu A, Okumus N, Polin RA: Randomized controlled trial of slow vs rapid enteral feeding advancements … Continue reading →

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Breast-feeding the preterm

Posted on 9 August 2013 by Keith Barrington

In order to catch up a little with the last month’s publications, I will post a few things with grouped studies that seem to me to be related. Alves E, Rodrigues C, Fraga S, Barros H, Silva S: Parents’ views … Continue reading →

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Probiotic Fungi too?

Posted on 4 June 2013 by Keith Barrington

It seems that probiotic fungi, specifically Saccharomyces boulardii probably don’t prevent NEC. There is one previous study Costalos et al which showed no difference in NEC, but some benefits on secondary outcomes (it was very underpowered for NEC, 87 babies … Continue reading →

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Probiotics in the NICU: a ‘how-to’ guide

Posted on 22 May 2013 by Keith Barrington

I have had several communications from people interested in starting the use of probiotics in their nurseries. There are often roadblocks, and some reluctance from either infection control, or pharmacy and therapeutics committees (or both). I will recount what we … Continue reading →

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Probiotics work in Practice

Posted on 19 May 2013 by Keith Barrington

For anyone who was at the latest PAS meeting, you probably heard about the presentation of Proprems. This is the latest RCT of probiotics, from Australia and New Zealand, using ABCDophilus, which is interestingly manufactured in New Jersey. The authors … Continue reading →

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