Tag Archives: long term outcomes

Glutamine supplementation, just when you thought it was solved…

Posted on 24 October 2012 by Keith Barrington

Glutamine is one of the most abundant amino acids in our bodies, but there is relatively little in TPN as it is poorly soluble. During the first few days of limited enteral nutrition preterm babies receive little glutamine from any … Continue reading →

Posted in Neonatal Research | Tagged , , , | 2 Comments

Outcomes of Prematurity… Pregnancy!

Posted on 26 September 2012 by Keith Barrington

One very long term outcome study of premature infants has just been published by my colleagues from Sainte Justine: Boivin A, Luo Z-C, Audibert F, Mâsse B, Lefebvre F, Tessier R, Nuyt AM: Pregnancy complications among women born preterm. Canadian Medical … Continue reading →

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A life worth living: myelomeningocele.

Posted on 10 September 2012 by Keith Barrington

Do handicapped persons’ lives have value? Even asking that question is offensive, at least to me, and I just asked it! It seems to me that much of the focus of programs of antenatal diagnosis is based on the premise … Continue reading →

Posted in Advocating for impaired children | Tagged , | 9 Comments

Predicting Long Term Outcomes: MRI at term for very preterm babies

Posted on 4 September 2012 by Keith Barrington

The most recent Acta Paediatrica includes 2 articles. One from parents of a very preterm infant that we looked after at Sainte Justine. They recount their experiences of having a baby at 25 weeks, and what happened to them when they had a brain … Continue reading →

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Improving outcomes of Preterm Infants, early post-discharge intervention programs

Posted on 8 August 2012 by Keith Barrington

The history of early intervention programs is rather mixed. Do they actually help to improve outcomes? The most recent cochrane review was published in 2007 by the amazingly productive Lex Doyle and his colleagues, and was followed by an updated review … Continue reading →

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A life worth living? Who would want a child like that?

Posted on 5 August 2012 by Keith Barrington

A troubling tale from an adult with a handicap has just been published. (Peace WJ: Comfort care as denial of personhood. Hastings Center Report 2012, 42(4):14-17.) When admitted to an acute care hospital with a serious wound the author was … Continue reading →

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Trying to improve outcomes of preterm infants

Posted on 17 July 2012 by Keith Barrington

Two recent RCTs in high risk newborns of things I would never have thought of. The first is a trial of Estradiol and Progesterone supplementation (Trotter A, Steinmacher J, Kron M, Pohlandt F. Neurodevelopmental Follow-Up at Five Years Corrected Age … Continue reading →

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Predicting outcomes: Adults vs Babies

Posted on 11 July 2012 by Keith Barrington

An interesting article in Archives of Internal Medicine (Chan PS, Spertus JA, Krumholz HM, Berg RA, Li Y, Sasson C, Nallamothu BK, Investigators. GWTG-RR: A validated prediction tool for initial survivors of in-hospital cardiac arrest. Arch Intern Med 2012, 172(12):1-7. http://archinte.jamanetwork.com/article.aspx?articleid=1162169); … Continue reading →

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Outcomes of GBS meningitis; as good as 24 week premies.

Posted on 4 July 2012 by Keith Barrington

As several of you may know, I am co-author, with Annie Janvier, of a series of articles examining how our prejudices about the worth of individuals affect decision making in the critically ill. In some of those articles we compare … Continue reading →

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What next for birth asphyxia?

Posted on 27 June 2012 by Keith Barrington

Now that therapeutic hypothermia has been proven effective and safe for infants with Hypoxic Ischemic Encephalopathy, one might ask what next? We still are not sure if it is of any value to cool infants after 6 hours of age, … Continue reading →

Posted in Neonatal Research | Tagged , , | 2 Comments