Tag Archives: long term outcomes

Predicting outcomes, but not before birth

One very important article that I failed to blog about last year when it came out is this one (Ambalavanan N, Carlo WA, Tyson JE, Langer JC, Walsh MC, Parikh NA, Das A, Van Meurs KP, Shankaran S, Stoll BJ … Continue reading

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Does gestational age matter?

Taking a break from the SUPPORT brouhaha for a moment, here is a great systematic review from Greg Moore and colleagues in Ottawa. (Moore GP, Lemyre B, Barrowman N, Daboval T: Neurodevelopmental outcomes at 4 to 8 years of children … Continue reading

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Susceptibility to Sepsis

It looks like those Toll-like receptors may indeed be important. I included a review article in a previous Neonatal Updates, which was nice introduction to these transmembrane receptors that are important in immune responses. A new article suggests that variants … Continue reading

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End of Life, at Birth

An Op-Ed piece in the NY Times a couple of weeks ago had that title. I was rather disappointed by the piece, written by an experienced neonatologist; now I suppose for a piece written for the NY Times the fact … Continue reading

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Long term outcomes, Quality of Life.

I heard a presentation of this excellent study when I was in Melbourne last year, and have been waiting for it to be available in print. There are now about 30 studies of quality of life in subjects who were … Continue reading

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HIE: what’s next?

Kapadia VS, Chalak LF, Dupont TL, Rollins NK, Brion LP, Wyckoff MH: Perinatal Asphyxia with Hyperoxemia within the First Hour of Life Is Associated with Moderate to Severe Hypoxic-Ischemic Encephalopathy. The Journal of pediatrics 2013. If you are acidotic at … Continue reading

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ECMO: not dead yet

There is a sort of a quadruple entendre in the title of this post: ECMO still exists; ECMO is needed if you are ‘not yet dead’ and have a chance of surviving; ECMO decreases mortality if you need it; but, … Continue reading

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Speech is developing even before the speech centers appear

Someone who is more expert in this field than me could probably take apart that title, but the message of this article is that, even at 29 weeks gestation, , the preterm brain reacts differently to different phonemes (ba versus … Continue reading

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What we don’t know about neonatal endocrinology #3, the thyroid.

To finalize this litany of the unknown… We also need to know whether low thyroxine levels are common in the preterm (they are) what the consequences are (associated with worse long term outcomes) whether they are causative (don’t know) and … Continue reading

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Predicting outcomes in preterm infants: is it time to throw away the ultrasound machine?

It is common practice, nearly universal, I would guess, to perform head ultrasounds in the 1st week of life as a way to predict which very preterm babies will have very poor outcomes, and then to consider redirection of care … Continue reading

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