Tag Archives: BPD

Who should get surfactant?

Posted on 23 August 2013 by Keith Barrington

I think the literature is clear, if you need surfactant, the earlier you get it the better. If you don’t need surfactant you are better off never being intubated. So how do we decide? Current management protocols usually put babies … Continue reading →

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Acidosis and the preterm, effects on heart and lungs

Posted on 16 May 2013 by Keith Barrington

Noori S, Wu T-W, Seri I. pH Effects on Cardiac Function and Systemic Vascular Resistance in Preterm Infants. The Journal of pediatrics. 2013;162(5):958-63.e1. This study examined the effects of pH on ventricular outputs and calculated vascular resistance. There was little … Continue reading →

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How long is a piece of string? When is a PDA hemodynamically significant?

Posted on 16 February 2013 by Keith Barrington

The answer to the first question is traditionally ‘twice as long as half a piece of string’ which is supposed to be funny. Equally difficult is the second question, when is a patent ductus arteriosus (PDA)  hemodynamically significant? We could … Continue reading →

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Supporting oxygen limits

Posted on 19 January 2013 by Keith Barrington

The initial results of the SUPPORT trial examining the effects of different oxygen limits stopped a lot of us in our tracks. We started these trials because most of us thought that aiming for lower oxygen saturation targets would reduce … Continue reading →

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Trying to improve outcomes of preterm infants

Posted on 17 July 2012 by Keith Barrington

Two recent RCTs in high risk newborns of things I would never have thought of. The first is a trial of Estradiol and Progesterone supplementation (Trotter A, Steinmacher J, Kron M, Pohlandt F. Neurodevelopmental Follow-Up at Five Years Corrected Age … Continue reading →

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Fluid Restricting Babies: Part 2

Posted on 30 May 2012 by Keith Barrington

While I am on a roll… Fluid restriction as a means of treating babies with BPD makes no sense. It is also unsupported by any literature. I think this practice may have arisen because diuretics are given to infants with BPD (don’t get … Continue reading →

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Fluid Restricting Babies

Posted on 29 May 2012 by Keith Barrington

A study published online first in the Journal of Pediatrics questions a common practice, the practice of fluid restricting babies who have a patent ductus arteriosus. De Buyst J, Rakza T, Pennaforte T, Johansson AB, Storme L: Hemodynamic Effects of … Continue reading →

Posted in Neonatal Research | Tagged , , , , , | 5 Comments