Category Archives: Neonatal Research

High Frequency Ventilation and long term pulmonary outcomes

Posted on 6 May 2014 by Keith Barrington

The UK Oscillation study (UKOS) was a large multicenter trial in the UK of high-frequency compared to conventional ventilation; 800 babies <29 weeks gestation were randomized, if they were intubated from birth and were less than 1 hour old, to … Continue reading →

Posted in Neonatal Research | Tagged , , | Leave a comment

Annual PAS meeting

Posted on 6 May 2014 by Keith Barrington

Just home after an extremely busy, as usual, PAS meeting In Vancouver. Please sir, can I be excused, my brain is full. I will blog a bit about it in the next few days, in the mean time, I will … Continue reading →

Posted in Neonatal Research | Leave a comment

High Flow Nasal Cannulae: poor man’s CPAP?

Posted on 1 May 2014 by Keith Barrington

The title is how I sometimes refer to HFNC, but one could ask whether that is all there is to high flow, is it just another way to deliver CPAP, but with no control, or knowledge, of the pressure delivered? … Continue reading →

Posted in Neonatal Research | Tagged , , , , | 2 Comments

Executive Function?

Posted on 29 April 2014 by Keith Barrington

Raju TNK, Mercer BM, Burchfield DJ, Joseph GF. Periviable birth: executive summary of a Joint Workshop by the Eunice Kennedy Shriver National Institute of Child Health and Human Development, Society for Maternal-Fetal Medicine, American Academy of Pediatrics, and American College … Continue reading →

Posted in Neonatal Research | Tagged , , , | 1 Comment

Necrotising Enterocolitis: is abdominal ultrasound helpful?

Posted on 29 April 2014 by Keith Barrington

I am still not convinced. (Maybe I could ask, and answer, the same thing about abdominal radiography!) In recent years in my practice we have had examples of echographic diagnosis of intramural gas in stable infants who had an abdominal … Continue reading →

Posted in Neonatal Research | Tagged , , | Leave a comment

Better research, for better care

Posted on 28 April 2014 by Keith Barrington

I hope this commentary in JAMA receives a lot of ‘likes’! Eapen ZJ, Lauer MS, Temple RJ. The imperative of overcoming barriers to the conduct of large, simple trials. JAMA. 2014;311(14):1397-8. The commentary includes a report of a conference about … Continue reading →

Posted in Neonatal Research | Leave a comment

Retraction of a systematic review

Posted on 28 April 2014 by Keith Barrington

Exactly when should an article be retracted? That is not so easy a question to answer, fraud and significant data or image manipulation are one fairly obvious group of reasons. Making errors and/or poor research design are more tricky. When … Continue reading →

Posted in Neonatal Research | Tagged , , | Leave a comment

Neonatal Updates

Posted on 27 April 2014 by Keith Barrington

Corvaglia L, Martini S, Battistini B, Rucci P, Aceti A, Faldella G. Bolus versus continuous feeding: effects on splanchnic and cerebral tissue oxygenation in healthy preterm infants. Pediatr Res. 2014. During a 6 hour period, preterm infants had either a … Continue reading →

Posted in Neonatal Research | Tagged | Leave a comment

Pulse Oximetry Screening : It’s About Time

Posted on 27 April 2014 by Keith Barrington

It is about time! Timely diagnosis, and timely intervention for children with potentially lethal cardiac defects make an enormous individual difference to their survival and other outcomes. A new enormous study in the lancet from China (over 120,000 babies screened) … Continue reading →

Posted in Neonatal Research | Leave a comment

Treating pneumothoraces? Either a tube or leave them alone.

Posted on 21 April 2014 by Keith Barrington

I never understood why it was recommended to give 100% oxygen to treat a pneumothorax. I think the idea was that the gas in the pneumothorax could be replaced by oxygen which would then be reabsorbed more quickly if we … Continue reading →

Posted in Neonatal Research | Tagged , | Leave a comment