Author Archives: Keith Barrington

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About Keith Barrington

I am a neonatologist and clinical researcher at Sainte Justine University Health Center in Montréal

Domperidone for GE reflux; toxic and worse than placebo!

Posted on 6 October 2012 by Keith Barrington

As mentioned in a previous post, to get cisapride for a patient in Canada, you have to contact Health Canada for special permission through the Special Access Program. The last time that I am aware of someone asking Health Canada for special … Continue reading →

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Cisapride for GE reflux; more toxic placebos!

Posted on 6 October 2012 by Keith Barrington

I am currently writing a chapter for a textbook, the chapter will deal with GE reflux. So I have been reviewing the data around various treatment options. I have already written on this blog about the lack of physiologic rationale … Continue reading →

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Weekly updates #9

Posted on 6 October 2012 by Keith Barrington

Avettand-Fenoel V, Marlin S, Vauloup-Fellous C, Loundon N, Francois M, Couloigner V, Rouillon I, Drouin-Garraud V, Laccourreye L, Denoyelle F et al: Congenital Cytomegalovirus Is the Second Most Frequent Cause of Bilateral Hearing Loss in Young French Children. J Pediatr … Continue reading →

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Do blood transfusions improve feeding in anemic preterm Infants?

Posted on 2 October 2012 by Keith Barrington

The possible benefits of blood transfusions in anemic preterm infants have never been well investigated. There is some reliable data about the outcomes of babies randomized to different goals of hemoglobin concentration (for example the PINT study Kirpalani H, Whyte RK, Andersen C, Asztalos EV, … Continue reading →

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Improving Nutrition in the very Preterm; more protein?

Posted on 1 October 2012 by Keith Barrington

A new study published in Pediatrics looked at the question in the title of this post. Moya F, Sisk PM, Walsh KR, Berseth CL: A new liquid human milk fortifier and linear growth in preterm infants. Pediatrics 2012.  This was a … Continue reading →

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Weekly Updates #8

Posted on 29 September 2012 by Keith Barrington

Oei JL, Kingsbury A, Dhawan A, Burns L, Feller JM, Clews S, Falconer J, Abdel-Latif ME: Amphetamines, the pregnant woman and her children: a review. J Perinatol 2012, 32(10):737-747.  This review article notes the limited evidence about the perinatal effects … Continue reading →

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More sweetness, some light?

Posted on 27 September 2012 by Keith Barrington

The latest NEJM has an article addressing an issue that I recently posted about, glucose control in the critically ill. This study was in 980 children less than 3 years of age who had undergone cardiac surgery in 2 centers … Continue reading →

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Outcomes of Prematurity… Pregnancy!

Posted on 26 September 2012 by Keith Barrington

One very long term outcome study of premature infants has just been published by my colleagues from Sainte Justine: Boivin A, Luo Z-C, Audibert F, Mâsse B, Lefebvre F, Tessier R, Nuyt AM: Pregnancy complications among women born preterm. Canadian Medical … Continue reading →

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Weekly updates #7

Posted on 25 September 2012 by Keith Barrington

Jain A, Deshpande P, Shah P: Peripherally inserted central catheter tip position and risk of associated complications in neonates. J Perinatol 2012. This retrospective cohort study showed more complications when catheters were mid-clavicular, in terms of infiltration, breakage and leaking, … Continue reading →

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Sweet!

Posted on 24 September 2012 by Keith Barrington

Very immature babies often become hyperglycemic during the first few days of life. How to respond (or prevent) this has been uncertain. One problem in deciding on the best course of action is the multiple possible approaches that need to … Continue reading →

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