Monthly Archives: November 2024

Surfactant plus Budesonide? Not a PLUSS for outcomes

Many of us were already aware of the general direction of the results of this trial, a multi-centre RCT of surfactant with or without budesonide (Manley BJ, et al. Intratracheal Budesonide Mixed With Surfactant for Extremely Preterm Infants. JAMA. 2024), … Continue reading

Posted in Neonatal Research | Tagged , , , , | 2 Comments

What Sick Babies Can Teach Us

As usual for a TED talk this is 18 minutes long, and, in that brief time, Annie recounts her trajectory: learning from families of kids with trisomy 13 and trisomy 18; our own experience with counselling for threatened extreme preterm … Continue reading

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Surgery for NEC; enterostomy or anastomosis?

There are only a few randomized trials in neonatal surgery, but those that exist have had a major impact. This new publication may do the same, even though the sample size is relatively modest, and there are some issues with … Continue reading

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The nicuverse and 99NICU

As some of you may have noticed, I left Twitter (X), apart from sending a link to each new post on this blog. I never any longer visit the website and I have deleted the App on my phone. A … Continue reading

Posted in Neonatal Research | 1 Comment

Making Clinical Research Oversight Fit-for-Purpose

The title is a slightly edited copy of the title a discussion article in JAMA, that discusses some important issues in IRB oversight of clinical research. (Kass NE, et al. Making the Ethical Oversight of All Clinical Trials Fit for … Continue reading

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