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Recent Posts
- The role of Ureaplasma in Chronic Lung Disease of Prematurity
- Intravenous Nutrition of the sick term and late preterm infants : part 2.
- Intravenous Nutrition of sick term and late preterm infants : part 1.
- Nasal intubation improves feeding outcomes
- Vitamin A for prevention of lung disease in the preterm
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Author Archives: Keith Barrington
The role of Ureaplasma in Chronic Lung Disease of Prematurity
There have long been questions about the possible role of ureaplasma in the pathogenesis of BPD. Studies have shown a statistical association between maternal colonization and BPD, between placentas showing evidence of the germ, and between neonatal endotracheal colonization and … Continue reading
Intravenous Nutrition of the sick term and late preterm infants : part 2.
The other trial is a much larger multicentre trial with clinical outcomes. (Alexander T, et al. Nutritional Support for Moderate-to-Late-Preterm Infants – A Randomized Trial. N Engl J Med. 2024;390(16):1493-504), the gestational ages only overlapped by 1 week with the … Continue reading
Posted in Neonatal Research
Tagged Parenteral Nutrition, Randomized Controlled Trials, Sepsis
1 Comment
Intravenous Nutrition of sick term and late preterm infants : part 1.
There are 2 new trials addressing different aspects of the questions surrounding what to do about TPN for this group of babies. My readers may remember my post about the PEPaNIC trial, which showed that there were disadvantages of early … Continue reading
Posted in Neonatal Research
Tagged Parenteral Nutrition, Randomized Controlled Trials, Sepsis
1 Comment
Nasal intubation improves feeding outcomes
The title of the post sneakily did not mention that I am referring to a study in a specific subgroup of babies, the paper is a report of an RCT in newborn infants who had heart surgery. Yildirim MI, et … Continue reading
Vitamin A for prevention of lung disease in the preterm
Previous studies have shown that vitamin A supplementation can reduce the frequency of BPD, but the practice has not become widespread. In part, I think, it is because repeated intramuscular injections of vitamin A are the route that has been … Continue reading
PAS meeting 2024: The Silverman Lecture
For those who are unaware, the Silverman Lecture is an annual honour bestowed by the AAP. A neonatologist who has made. or is making, major impacts in neonatology is asked to deliver the lecture. Bill Silverman was one of the … Continue reading
PAS report 2024: Alan Jobe
There was a hiccup yesterday, I was writing the part 2 and it suddenly got posted as just the title, and the entire post disappeared. I had to start all over (which has never happened before, there are usually automatic … Continue reading
Posted in Neonatal Research
1 Comment
PAS report 2024: Clinical Trials part 2
The NeoGluCO trial This trial was a modestly sized RCT of low dose diazoxide for treatment of persistent or severe hypoglycaemia in newborn infants of at least 35 weeks gestation. I say “modestly sized” as a descriptor, not a criticism, … Continue reading
PAS report 2024: Clinical Trials part 1.
As usual the PAS meeting was packed with neonatology. The App was even worse than last year, crashing frequently on many peoples’ phones. It was completely useless for the posters, as they were listed by number, and the different sessions … Continue reading
Not neonatology. Birding in western Ontario
On my way to the PAS annual meeting in Toronto, I decided to spend a couple of days at Point Pelee national park. It is the southern-most point of Canada, a peninsula jutting out into lake Erie that is a … Continue reading
Posted in Neonatal Research
5 Comments