Tag Archives: Systematic Reviews

Three new publications

The latest issue of Seminars in Perinatology has just appeared on line. This is second part of the report of the NICHD, SMFM, ACOG, AAP joint workshop where Annie and I presented. I think these articles are all free access: … Continue reading

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NIDCAP, battling systematic reviews.

I mentioned Arne Ohlsson’s review of the NIDCAP studies in a previous post. A new systematic review comes to different conclusions. This review (Fazilleau L, Parienti JJ, Bellot A, Guillois B: Nidcap in preterm infants and the neurodevelopmental effect in … Continue reading

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Reducing BPD by Avoiding Intubation

Sometimes more than one article gets published almost simultaneously on the same topic, sometimes with similar methodology. Two systematic reviews of the effects of trying to avoid or curtail endotracheal intubation in order to protect the lungs have just been … Continue reading

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Pain hurts

In 2010 a paper published in the Lancet called into question the use of sucrose as an analgesic for heelsticks. (I will use the US term as I think most people understand that it refers to lancing the heel of … Continue reading

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Does gestational age matter?

Taking a break from the SUPPORT brouhaha for a moment, here is a great systematic review from Greg Moore and colleagues in Ottawa. (Moore GP, Lemyre B, Barrowman N, Daboval T: Neurodevelopmental outcomes at 4 to 8 years of children … Continue reading

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Is volume ventilation really better?

A systematic review published in 2011 of the studies comparing pressure to volume ventilation stated that there was ‘reduced death/BPD, duration of ventilation, pneumothoraces, hypocarbia and periventricular leukomalacia/severe intraventricular hemorrhage’ using volume targeted ventilation.’ I think it may be true that volume ventilation … Continue reading

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HIE: what’s next?

Kapadia VS, Chalak LF, Dupont TL, Rollins NK, Brion LP, Wyckoff MH: Perinatal Asphyxia with Hyperoxemia within the First Hour of Life Is Associated with Moderate to Severe Hypoxic-Ischemic Encephalopathy. The Journal of pediatrics 2013. If you are acidotic at … Continue reading

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Probiotic Fungi too?

It seems that probiotic fungi, specifically Saccharomyces boulardii probably don’t prevent NEC. There is one previous study Costalos et al which showed no difference in NEC, but some benefits on secondary outcomes (it was very underpowered for NEC, 87 babies … Continue reading

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Predicting outcomes in preterm infants: is it time to throw away the ultrasound machine?

It is common practice, nearly universal, I would guess, to perform head ultrasounds in the 1st week of life as a way to predict which very preterm babies will have very poor outcomes, and then to consider redirection of care … Continue reading

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Does NIDCAP work?

I guess that depends on what you mean ‘work’.  Does developmentally sensitive care lead to more responsive, humane, and less disturbing care, improving the environment for our preterm infants, I think the answer is clearly yes. If you mean does … Continue reading

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