Tag Archives: Randomized Controlled Trials

Zinc supplementation: should we be galvanized into action?

I wasn’t sure how many non native-English speakers would get that joke, and jokes are rarely improved by explaining them, so if you don’t get it, just keep on reading. Terrin G, Berni Canani R, Passariello A, Messina F, Conti … Continue reading

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Oxygen, transfusions, and NEC

What causes NEC! The answer is ‘who knows?’, or perhaps a better one would be ‘its complicated…’ You probably need an immature gut, gut mucosal injury, inflammation and cytokine release, and an abnormal microbiome, all of which probably interact in … Continue reading

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Septic Shock; 3 negative trials

Three trials back to back in the PNEJM (that’s the prestigious New England Journal of Medicine for any new readers) in adults with septic shock are disappointing: Early Goal Directed Therapy has become a dogma in recent years; it even … Continue reading

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Sticking needles into babies doesn’t reduce colic. Who’d have thought…

More nonsense, this time acupuncture for babies! Ninety babies were randomized in a multicenter trial of sticking needles into non-existent meridians to channel imaginary Qi energy. Unfortunately the condition they were investigating, infantile colic, causes a lot of real distress … Continue reading

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Waving your hands around is not analgesic! Who’d have thought…

Really, who’d have thought it was worth testing. I have a lot of respect for several of the authors of this trial, but I can’t for the life of me understand why they did this study. Celeste Johnston, Marsha Campbell-Yeo, … Continue reading

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Public citizen are becoming a public danger

Public citizen are at it again, they have written another letter to the director of the DHHSS to try and follow up on their previous nonsense. I didn’t write about this when I first heard about it, as 1. it … Continue reading

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HIP Protocol published

The Hypotension in Preterms trial is about to get underway, with all the final hurdles just about cleared. Just at the right time our protocol has been published in ‘Neonatology’. Dempsey EM, Barrington KJ, Marlow N, O’Donnell CP, Miletin J, … Continue reading

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Leave my renal nerves alone, please.

Not having looked after an adult for many years (although I did do a year of postgraduate training in adult internal medicine before switching to paediatrics; I thought I should practice on the old ones before subjecting children to my … Continue reading

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More about mother’s voices

When I first read this article I thought that the authors had rigged up a system to play music actually in the babies mouth, but I think I was wrong about that. Chorna OD, Slaughter JC, Wang L, Stark AR, … Continue reading

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Does being ventilated hurt? It depends who you ask

Ruth Guinsburg is a neonatologist in Sao Paulo who has been super-productive, especially in the area of pain control in the newborn. Her latest is an interesting comparison of how caregivers and parents rate pain in infants on ventilators. Elias … Continue reading

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