Tag Archives: pulmonary physiology

High Frequency Ventilation and long term pulmonary outcomes

The UK Oscillation study (UKOS) was a large multicenter trial in the UK of high-frequency compared to conventional ventilation; 800 babies <29 weeks gestation were randomized, if they were intubated from birth and were less than 1 hour old, to … Continue reading

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Ventilator Graphics: Are Pressure Volume Loops interesting?

If you buy a new ventilator today for your preterm infants, you cannot avoid having ‘sophisticated graphics’. These ‘sophisticated graphics’ are supposed to help you ventilate the babies appropriately. I have always been very skeptical about ‘sophisticated graphics’ as they … Continue reading

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PEEP and ductal shunts

I never thought that modest increase in PEEP would have a real effect on ductal shunting. As the size of the ductal shunt depends on the pressure gradient across the PDA and the resistance of the vessel, in order to … Continue reading

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Pulmonary compliance changes after surfactant

This blog is a bit different: not a review of a recent publication, but rather a teaching point for my junior trainees (and maybe some seniors). The question is this: when you have preterm infant with typical HMD and respiratory … Continue reading

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