Tag Archives: Probiotics

Probiotics work in Germany also

A new study from the German Neonatal Network Database compares the incidence of NEC between centers that used probiotics, centers that did not use probiotics, and centers that changed their practice part way through the data collection period from being … Continue reading

Posted in Neonatal Research | Tagged , | 2 Comments

Probiotics in preterm infants: not just for NEC prevention any more

A new RCT in more mature preterm infants 32 to 37 weeks compared the incidence of viral respiratory infections during the first year of life between infants who received prebiotics (galacto-oligosaccharide and polydextrose) probiotics (lactobacillus rhamnosus) or placebo between the … Continue reading

Posted in Neonatal Research | Tagged , | Leave a comment

Probiotics: what do parents want?

Some day, I might slow down with the probiotics posts, but not right now! A letter published in Archives reports the results of a parent survey. In the 3 NICUs implicated probiotics are given with parental information and an ‘opt-out’ … Continue reading

Posted in Neonatal Research | Tagged , , | Leave a comment

Bugs and Breast Milk

Neonatology recently published a commentary asking the following question about routine probiotic supplementation, ‘what will it take to change practice?‘ This was immediately followed by another commentary, from Neena Modi, explaining why she is still reluctant. Although I have a … Continue reading

Posted in Neonatal Research | Tagged , , | 2 Comments

Stop the Antibiotics!

We know that prolonged antibiotic use in preterm babies increase their chance of later developing NEC. The assumption being that the disturbance of the intestinal flora leads to the increase in susceptibility. Here is some more direct evidence to support … Continue reading

Posted in Neonatal Research | Tagged , , | 4 Comments

Yet more probiotic stuff

Here is the other study of saccharomyces that I mentioned previously on this blog (Demirel G, Erdeve O, Celik IH, Dilmen U: Saccharomyces boulardii for prevention of necrotizing enterocolitis in preterm infants: A randomized, controlled study. Acta Paediatrica 2013) recently … Continue reading

Posted in Neonatal Research | Tagged , , , | Leave a comment

Probiotics : Time for Action

As I have noted before on this blog, our article showing the effects of the introduction of routine probiotics in our NICU has been published on-line. The Journal of Pediatrics decided to accompany it with an editorial by William Tarnow-Mordi … Continue reading

Posted in Neonatal Research | Tagged , , | 2 Comments

Cohort study of Probiotics in our NICU

Our article describing the results of introducing routine probiotic prophylaxis in our NICU has just become available on-line. Janvier A, Malo J, Barrington KJ: Cohort Study of Probiotics in a North American Neonatal Intensive Care Unit. The Journal of pediatrics … Continue reading

Posted in Neonatal Research | Tagged , , | 2 Comments

Probiotics work, they really, really, work! (And they are safe)

The Proprems study that I have referred to a couple of times before has now been published. This was a multicenter RCT of a probiotic preparation in 1100 very preterm infants less than 1500 grams and less than 32 weeks. … Continue reading

Posted in Neonatal Research | Tagged , , | Leave a comment

Do Probiotics prevent C difficile?

My recent post about Bayesian analysis was in part prompted by this trial, just published in the Lancet, but I never got back to discussing this trial, being distracted by other things, like actual work. Nearly 3000 adults were randomized … Continue reading

Posted in Neonatal Research | Tagged , | Leave a comment