Tag Archives: Probiotics

Probiotics: what do parents want?

Some day, I might slow down with the probiotics posts, but not right now! A letter published in Archives reports the results of a parent survey. In the 3 NICUs implicated probiotics are given with parental information and an ‘opt-out’ … Continue reading

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Bugs and Breast Milk

Neonatology recently published a commentary asking the following question about routine probiotic supplementation, ‘what will it take to change practice?‘ This was immediately followed by another commentary, from Neena Modi, explaining why she is still reluctant. Although I have a … Continue reading

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Stop the Antibiotics!

We know that prolonged antibiotic use in preterm babies increase their chance of later developing NEC. The assumption being that the disturbance of the intestinal flora leads to the increase in susceptibility. Here is some more direct evidence to support … Continue reading

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Yet more probiotic stuff

Here is the other study of saccharomyces that I mentioned previously on this blog (Demirel G, Erdeve O, Celik IH, Dilmen U: Saccharomyces boulardii for prevention of necrotizing enterocolitis in preterm infants: A randomized, controlled study. Acta Paediatrica 2013) recently … Continue reading

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Probiotics : Time for Action

As I have noted before on this blog, our article showing the effects of the introduction of routine probiotics in our NICU has been published on-line. The Journal of Pediatrics decided to accompany it with an editorial by William Tarnow-Mordi … Continue reading

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Cohort study of Probiotics in our NICU

Our article describing the results of introducing routine probiotic prophylaxis in our NICU has just become available on-line. Janvier A, Malo J, Barrington KJ: Cohort Study of Probiotics in a North American Neonatal Intensive Care Unit. The Journal of pediatrics … Continue reading

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Probiotics work, they really, really, work! (And they are safe)

The Proprems study that I have referred to a couple of times before has now been published. This was a multicenter RCT of a probiotic preparation in 1100 very preterm infants less than 1500 grams and less than 32 weeks. … Continue reading

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Do Probiotics prevent C difficile?

My recent post about Bayesian analysis was in part prompted by this trial, just published in the Lancet, but I never got back to discussing this trial, being distracted by other things, like actual work. Nearly 3000 adults were randomized … Continue reading

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Prebiotics, to support growth of Probiotics, and how to kill them

Ishizeki S, Sugita M, Takata M, Yaeshima T: Effect of administration of bifidobacteria on intestinal microbiota in low-birth-weight infants and transition of administered bifidobacteria: A comparison between one-species and three-species administration. Anaerobe 2013, 23(0):38-44. In this study the investigators report 3 … Continue reading

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Probiotic Fungi too?

It seems that probiotic fungi, specifically Saccharomyces boulardii probably don’t prevent NEC. There is one previous study Costalos et al which showed no difference in NEC, but some benefits on secondary outcomes (it was very underpowered for NEC, 87 babies … Continue reading

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