Tag Archives: Necrotising Enterocolitis

PPIs are toxic

PPIs could mean “public-private initiatives” which are highly toxic, as recent experience in the UK and in Quebec has shown, but in this case I mean proton pump inhibitors. Stark CM, Nylund CM. Side Effects and Complications of Proton Pump … Continue reading

Posted in Neonatal Research | Tagged , | Leave a comment

Prebiotics, Probiotics and the microbiome

A series of interesting recent articles: Yang J, et al. Application of Laser Capture Microdissection and 16S rRNA Gene Polymerase Chain Reaction in the Analysis of Bacteria Colonizing the Intestinal Tissue of Neonates With Necrotizing Enterocolitis. Pediatr Infect Dis J. … Continue reading

Posted in Neonatal Research | Tagged , , | Leave a comment

Do Blood transfusions trigger NEC? This month the answer is no.

OK, not exactly this month, but “towards the end of last year” wouldn’t have been as good a title. Three case-control studies, with some differences in design and implementation, but all 3 with the same result, no evidence that red … Continue reading

Posted in Neonatal Research | Tagged , | 1 Comment

NICUs are working better: still room for improvement.

As NICUs have become more effective, any proportional incremental improvements will necessarily get smaller, so larger and larger datasets will be needed to show any trends. The NICHD has just published data about survival and major acute morbidities among extremely … Continue reading

Posted in Neonatal Research | Tagged , , , , | Leave a comment

Re-re-re-visited (delayed cord clamping of course)

I received 2 comments about the last posting re: DCC. The way I set up this blog the comments aren’t necessarily very obvious, especially if you visit the home page rather than following a link to the individual posting. So I … Continue reading

Posted in Neonatal Research | Tagged , , , | 2 Comments

Genetic variants and NEC risk

This post is out of my usual comfort zone, but I thought I’d write about it as it is fascinating, and might lead to something clinical. I don’t understand any of the lab methodology of this study, except to say … Continue reading

Posted in Neonatal Research | Tagged , | 1 Comment

Delayed cord clamping or cord milking for the very preterm newborn… or both?

What should we be doing, given the current state of the evidence, for the very preterm neonate? I think the evidence is now pretty clear that full-term babies have benefits, and no significant harm, from delayed cord clamping, which has … Continue reading

Posted in Neonatal Research | Tagged , , , , | 6 Comments