Tag Archives: Hemodynamics

Low Cardiac Output after PDA ligation

Some babies after PDA ligation develop a low cardiac output, Patrick McNamara and his colleagues have defined that as being less than 200 mL/kg/min left ventricular output. This cohort study of 30 infants post-ligation, by Afif El-Khuffash and colleagues at … Continue reading

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Neonatal Updates : Therapeutic hypothermia

Three recent articles dealing with the effects of therapeutic hypothermia: Drury PP, Gunn ER, Bennet L, Gunn AJ. Mechanisms of Hypothermic Neuroprotection. Clin Perinatol. 2014;41(1):161-75. the first is an excellent review article describing how hypothermia works, SPOILER ALERT, its mostly … Continue reading

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Hypotension after PDA ligation

A new prospective multi-center evaluation, of cardiac function and the causes of hypotension after PDA ligation, has just published data about adrenal function. Clyman RI, et al: Hypotension following patent ductus arteriosus ligation: The role of adrenal hormones. The Journal … Continue reading

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HIP Protocol published

The Hypotension in Preterms trial is about to get underway, with all the final hurdles just about cleared. Just at the right time our protocol has been published in ‘Neonatology’. Dempsey EM, Barrington KJ, Marlow N, O’Donnell CP, Miletin J, … Continue reading

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Treatment of hypotension in the very preterm infant

When hypotension should be treated and with what are important and difficult questions in the care of the very preterm infant. The international HIP collaboration (see the link in the side bar) has been funded to try and find some … Continue reading

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PDA shunts and extubation

Following on from my recent post about PEEP levels and PDA shunts, this new article from Perth. The authors prospectively enrolled very immature infants (< 28 weeks) before a planned early extubation and did echocardiograms before and after. The mean … Continue reading

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PEEP and ductal shunts

I never thought that modest increase in PEEP would have a real effect on ductal shunting. As the size of the ductal shunt depends on the pressure gradient across the PDA and the resistance of the vessel, in order to … Continue reading

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Back Home

Back from Helsinki. The meeting was excellent, with a very high quality faculty, even though I diluted that down a little. I have put my presentation on this website, under ‘presentations from our group’ (link here). I presented on my … Continue reading

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What we don’t know about neonatal endocrinology #1, the adrenals.

I once wrote a paper with the last author of this article, when we were both working in Edmonton, so I will have to be nice, I guess. Seriously, we do need to know a lot more about adrenal responses … Continue reading

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Hypotension

A new study from the NICHD neonatal network Batton B, Li L, Newman NS, Das A, Watterberg KL, Yoder BA, et al. Use of Antihypotensive Therapies in Extremely Preterm Infants. Pediatrics. 2013 May 6.,This prospective cohort study was specifically designed … Continue reading

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