Tag Archives: BPD

Inhaled Nitric Oxide in Preterms

Kinsella JP, Cutter GR, Steinhorn RH, Nelin LD, Walsh WF, Finer NN, et al. Noninvasive Inhaled Nitric Oxide Does Not Prevent Bronchopulmonary Dysplasia in Premature Newborns. The Journal of pediatrics. 2014. My Cochrane review (which is in the process of being … Continue reading

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Sniffing out lung injury

Apparently exhaled breath analysis can be used to detect a number of pulmonary and systemic diseases. As a medical student I was taught  about some of the classical clinical signs of certain diseases (such as diabetic ketoacidosis) which make the … Continue reading

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More from SUPPORT, not research governance and consent this time!

One of the difficulties in performing neonatal research is how to determine the most clinically appropriate outcomes. Bronchopulmonary dysplasia is often used as a dichotomous outcome variable, partly to facilitate the design of research, including combining it with other competing outcomes, … Continue reading

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Stem Cells for BPD, we might be getting there, but without the cells

The development of this field has been fascinating, one of the most productive investigators has been Bernard Thébaud who has just written a very clear review article for non cell researchers in Pediatric Research with his colleague Moses Fung. (Fung … Continue reading

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The PDA, indomethacin and pulmonary hemorrhages.

In a comment on a recent post, Martin Kluckow pointed out that they have just had published a moderately sized RCT. It was supposed to be larger, but intravenous indomethacin became unavailable, so they had to stop the trial. (Kluckow … Continue reading

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Reducing BPD by Avoiding Intubation

Sometimes more than one article gets published almost simultaneously on the same topic, sometimes with similar methodology. Two systematic reviews of the effects of trying to avoid or curtail endotracheal intubation in order to protect the lungs have just been … Continue reading

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High Flow Nasal Cannulae; finally learning about them

The Melbourne group must get fed up of publishing important research, here is another in the PNEJM. Manley BJ, Owen LS, Doyle LW, Andersen CC, Cartwright DW, Pritchard MA, Donath SM, Davis PG: High-flow nasal cannulae in very preterm infants … Continue reading

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